Update 11/24/14   Clinical Diagnostics and Tools Stocks

  • Review Performance YTD and compared to 11/13 YTD
  • Top winners YTD are: EXAS 104%, ILMN 71.4%, ABAX 36.8%
  • Top Losers YTD are: NSTG 16.6%, RGDX 54%, VRML 30.9% but all were good trades.
  • IWM at $117.4

See Performance Data Below

———————-Previous post———

April Sell-Off Hit Diagnostic Small and Mid Caps

The bursting of the biotech bubble affected many small cap growth stocks. 2013 was a great year for our portfolio so some weakness was expected after the huge Q1 2014 moves. Most of our picks peaked in Jan/Feb time frame when many of our favorites were hit hard by profit taking. Follow technicals before adding new positions and watch small cap ETFs such as IWM ($111), IWO  ($127) and VBK ($118.7) all down 3-5% YTD for recovery.

  • Cepheid (CPHD) peaked in March in the $55 range. It is holding the ~$40 bottom but is still expensive. It is a leading molecular Dx player with M&A potential.
  • Cardiovascular Systems (CSII) had a blow-off top near $37 and is down 24.5% YTD. Still a growth stock but wait for $24-26 gap to fill.
  • Quidel (QDEL) is down 29% YTD after a big revenue and earnings miss. Will need time to recover.
  • Response Genetics (RGDX) was crushed after missing revenues again. Nothing to do here but hold for LT recovery.

The life science sector is still very attractive long term per all of our previous posts because of important trends : companion diagnostics, pharmaco-genomics,sequencing, point of care Dx and molecular Dx.

  • Illumina Inc. (ILMN) is a long term play in sequencing and has 90% of the market with ThermoFisher(TMO) as the only major competitor. It is a momentum stock that was hit by profit taking in $180 range but is starting to recover.  Strong hold with a buy on weakness.
  • Sequenom Inc.(SQNM) and Vermillion (VRML) have both recovered and are always good for trades. Strong holds.
  • Hologic Inc. (HOLX) is a restructuring play with a reiterated buy in low $20s.
  • RocheHoldings (RHHBY) is a leading mega-cap drug and diagnostic core holding in a life science portfolio.
  • Trinity Biotech plc (TRIB) was added at $24.75.

A review of Q1 financial reporting will follow this week. Q to Q revenue growth is key for all of these stocks.

Rayno Diagnostics and Tools 2014         Prices/Performance Updated as of 12/24

2010-2014 Original Price Price % Price % RET Price’13 %RET Price’14 Price 12/24
DX and Tools Recomm Dec’10 Ret 1/2/13 2013 Nov12. YTD May 22. Price  %Ret YTD
Abaxis ABAX 2/2/09 15 26.85 79 37.8 36.7 35.45 -4.45 41.6 58.5  46
CardioV.Sys CSII 11/5/10 7.2 11.66 63 13 29.7 29.5 135 25.85 29.8  (13.2)
Cepheid CPHD 10/23/12 31 35.5 13 41.97 24 42.6 53.4  14.4
Exact Sci EXAS 12/10/10 5.6 5.98 6.8 11 36 11.52 8.78 13.77 27.6  135
GenomicH GHDX 2/26/13 29 27.24 6.3 34.45 26.5 26.9 32.4  10.8
GenProbe GPRO 2/2/09 45 58.35 30 acq
Hologic HOLX* 4/9/13 22 20 20.51 2.5 23.85 26.9  20.3
Illumina ILMN 2/2/09 29 63.34 118 55.4 81.8 96.52 73.6 155.9 186.2  68.4
Alere ALR 2/2/09 25 36.6 46 19 -17.7 33.57 81.5 35.3 37.5  3.5
NeoGen NEOG 7/2/10 26 41.03 58 45.6 48.8 46.78 3.22 37.1 48.2  5.5
NanoString NSTG 11/21/13 12 11.3 14.8 13.9  (19.2)
Qiagen QGEN 3/15/10 22 19.55 -9 18.8 36 22.95 26.5 22.5 23.2  (2.6)
Quidel QDEL 6/16/10 12 14.45 16 19.9 31.3 24.55 31.5 21.65 27.9  (9.8)
ResponseG RGDX 2/3/12 1.5 1.4 -12.9 1.25 -10 0.9 0.37  (68)  off
RocheHold RHHBY 1/30/14 67 37.44 34.3  (2.3)
Sequenom SQNM 11/18/09 3.8 8.03 114 4.93 10.8 2.29 -51.4 2.83 3.6  53.4
ThermoFish TMO** 7/25/12 54 65 44.5 97.69 53 116 127  13.9
Vermillion VRML 5/15/13 2.5 1.37 73 2.54 92 2.94 1.8  (23.3)
*HOLX acq GPRO
**TMO acq LIFE
 Foundation Med  FMI  New  24  0
 PacBiosci  PACB  New  7.46  42.6

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