Rayno Life Science Portfolios July 1, 2013 Update

Biotechnology Sector (IBB 178) Up Over 30% YTD 

Many Rayno Focus Stocks Outperformed the Market

NASDAQ 3431 , S&P 1615

Biopharmaceutical-Top 5 Stocks- % Up YTD

  • Albany Molecular (AMRI) 140.7
  • Alkermes (ALKS) 59.3
  • Astex (ASTX) up 49.5
  • Biogen Idec (BIIB) up 48.9
  • Pharmacyclics (PCYC) up 47.8

Laggards: Alexion (ALXN), Exelixis (EXEL), Achillion (ACHN)

Diagnostics and Tools-Top 5 Stocks-% Up YTD

  • CardioVascular Systems (CSII) 69.6
  • Quidel (QDEL) 41.7
  • Illumina (ILMN) 37.2
  • Exact Sciences (EXAS) 36.4
  • ThermoFisher (TMO) 35.4

Laggards: Hologic (HOLX), Sequenom (SQNM)

BG Medicine and Vermillion (VRML) are new picks and volatile.

 Biopharmaceutical Stocks

2013 Price Original P Price %Ret Price Price % Ret Price
Summary Jy’10 Recomm Dec’10 2010 Apr’11 Dec’12 YTD’13 Jy1,’13
Achillion ACHN 3/4/13 8.6 4.37 8.36
Alexion ALXN 50.45 2/2/09 35 80.6 130 100.8 95.4 2.26 95.86(sp)
Alkermes ALKS 3/22/13 23 18.5 59.29 29.5
Albany Mol AMRI 2/10/11 4.68 added 4.32 5.3 140.7 12.71
Astex ASTX 12/27/11 1.63 2.7 49.48 4.35
Amgen AMGN 51.7 2/2/09 55 54.9 0 54 87.4 13.1 97.49
Biogen BIIB 49.42 2/2/09 48.5 67.1 37 73.25 149 48.85 217.88
Cephalon CEPH 55.95 2/2/09 76.5 61.7 -19 76.92 80.18 30 acquired
Cubist CBST 20.7 2/2/09 21.5 21.4 -3 28.35 42.4 19.2 50.11
Exelixis EXEL trade 9/2/10 3.3 8.21 148 11.12 4.58 1.97 4.66
First Trust FBT 30.4 4/15/10 37.5 39.1 3 41.3 46 29.6 59.57
Gilead GILD 34.9 2/2/09 51 36.2 -29 42.81 72.7 40.67 51.65(sp)
iShares ETF IBB 76.6 2/2/09 70.5 93.4 32 101.1 137.8 29.9 178.26
SPDR Bio XBI 86.38 23.7 108.73
Micromet MITI 6.28 2/2/09 4 8.12 103 5.46 10.91 272 acquired
ImmunoGen IMGN 12/22/11 12.4 12.5 34.8 17.19
Optimer OPTR trade 2/18/11 11.8 added 13.8 9.2 60 14.5
Pharmacycl PCYC 6/8/12 38.2 58 47.8 85.39
Regeneron REGN 21.6 2/2/09 17.5 32.8 82 45.43 173 34.5 230.14
Seattle Gen. SGEN 11.85 2/2/09 9.5 15 57 15.72 23.3 41 32.71
ViroPharma VPHM 10.88 2/2/09 12 17.3 44 20.05 22.9 29.4 29.45
Paired Trades
Pharmacycl PCYC long 6/8/12 38.2 60 51 85.39
Medivation MDVN short 6/8/12 86.8 closed 50 7 52(split)
net 58
Alkermes ALKS long 3/22/13 23 18.5 27 29.5
Infinity INFI short 3/22/13 48.7 closed 35 18 16.6
net 45

Diagnostics and Tools Stocks

2010-2013 Original Price Price % Price Price % RET Price %RET
DX and Tools Recomm Dec’10 Ret 10/2/12 1/2/13 1 yr 7/1/13 YTD
Abaxis ABAX 2/2/09 15 26.9 79 37.9 37.8 36.7 48.36 30.4
BG Medicine BGMD 5/15/13 1.73 NEW 2.32 -58 1.27 -45
CardioV.Sys. CSII 11/5/10 7.15 11.7 63 11.45 13 29.7 21.29 69.6
Celera CRA 3/28/10 7 6.3 18 acquired
Cepheid CPHD 10/23/12 31.4 NEW 35.5 13 34.72 2.54
Exact Sci EXAS 12/10/10 5.6 5.98 6.8 11.36 11 36 14.44 36.4
GenomicH GHDX 2/26/13 28.5 NEW 27.24 6.3 32.85 20.6
GenProbe GPRO 2/2/09 45 58.4 30 82.55 acquired
Hologic HOLX 4/9/13 21.6 NEW 20 19.57 -2.2
Illumina ILMN 2/2/09 29 63.3 118 51.2 55.4 81.8 76.27 37.2
Immucor BLUD 4/5/10 20 19.8 0 acquired
Alere ALR 2/2/09 25 36.6 46 19.64 19 -18 25.05 35.4
MicroFluidics MFLU 7/6/10 0.77 1.34 74 acquired
NeoGen NEOG 7/2/10 26 41 58 42.8 45.6 48.8 56.41 24.5
Qiagen QGEN 3/15/10 21.5 19.6 -9 19 18.8 36 20.05 10.5
Quidel QDEL 6/16/10 12.4 14.5 16 18.65 19.9 31.3 26.45 41.7
ResponseG RGDX 2/3/12 1.5 1.3 1.4 -13 1.52 9.35
Sequenom SQNM 11/18/09 3.75 8.03 114 3.5 4.93 10.8 4.3 -7.6
SeraCare SRLS 11/18/09 2.75 4.75 73 acquired
ThermoFish TMO 7/25/12 53.5 NEW 59.4 65 44.5 86.35 35.4
Vermillion VRML 5/15/13 2.53 NEW 1.37 73 2.65 101

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