Update-10/1 Rally Fades Early Today…NASDAQ Moves to Red
An early rally faded quickly today after an initial spike from new “NAFTA” deal. Biotech ETFs were red IBB down 0.63% and XBI down 1.34%.
- Mid-Cap biopharmas were mainly red with CAR-T and gene editing stocks hit hard: BLUE CRSP EDIT GWPH NTLA . Will provide news update.
- Some big Q3 winners were hit by profit taking: LOXO NKTR SRPT.
- Mid-Cap winners today: ALNY FOLD NBIX SGEN. Large caps held prices.
- Canadian cannabis stocks soared again today on trade agreement: NBEV,TLRY.
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Mid-Cap Biopharma Review 9/30/18
We first started following the Mid-Cap Biopharma sector in June 2018 when compelling ASCO clinical data rallied many stocks with strong oncology pipelines. Mid-Cap biopharma stocks tend to be more volatile and offer the potential for big gains because of breakthrough Phase 2 and Phase 3 clinical data and licensing agreements including M&A.
We have two stocks picks on the Mid-Cap Biopharma list: Foundation Medicine (FMI) which was acquired by Roche (RHHBY) and recently Tesaro (TSRO) which had fallen in just one year from over $100 to the $32 range. Based on technicals and fundamentals we felt TSRO offered good value with a strong balance sheet to execute their business strategy.
The stocks in this sector also offer a good indicator of overall biotechnology strength because of clinical news and deal announcements.
Top Five Winners YTD %
Serapta (SRPT). 177.2
Novacure (NVCR) 158
Intercept Pharma (ICPT) 124.25
Loxo Oncology (LOXO) 97.5
Xencor (XNCR). 70.9
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Top Five Losers
CRSPR Therapeutics (CRSP) -76.2
Clovis Oncology (CLVS) -55.5
Tesaro (TSRO -48.4
Exelixis (EXEL). -43.6
Alnylam (ALNY) -33.6
Have a look at the last column to see the stock trends over the last 3 mos.
Yahoo Finance offers a good platform for tracking stocks so paste this portfolio into Yahoo Finance and select appropriate metrics.
Disclosure: LONG FBIOX and TSRO and several other large and small caps.
| Company | Ticker | Price $ | Revs $B | MktCap | %Perf | Analyst | %Perf | |
| 9/28/18 | $B | YTD 2018 | Rating* | Q3 | ||||
| Acadia Pharma | ACAD | 20.76 | 0.185 | 2.59 | -31.8 | 2.1 | 37.76 | |
| Agio Pharma | AGIO | 77.12 | 0.07 | 4.5 | 28.9 | 2 | -6.89 | |
| Alnylam | ALNY | 87.52 | 0.107 | 8.87 | -33.6 | 2.1 | -9.93 | |
| Anaptys Bio | ANAB | 99.77 | 0.04 | 2.39 | 0.81 | 1.8 | 40 | |
| ArenaPharma | ARNA | 46.02 | 0.014 | 2.24 | 27.09 | 1.8 | 8.77 | |
| Array Biopharma | ARRY | 15.2 | 0.17 | 3.15 | 12.2 | 1.6 | -10.6 | |
| AveXis | AVXS | 217 | 0 | 8 | 96.2 | 2.8 |
acquired
|
|
| BlueBird Bio | BLUE | 146 | 0.036 | 7.99 | -19.7 | 2.1 | -5.87 | |
| Blueprint Med | BPMC | 78.06 | 0.17 | 3.43 | -2.44 | 1.6 | 28 | |
| Clovis Oncology | CLVS | 29.37 | 0.076 | 1.55 | -55.53 | 2.1 | -34.72 | |
| CRISPR Ther | CRSP | 44.35 | 0.037 | 2.3 | -76.2 | 2.3 | -24.6 | |
| Exelixis | EXEL | 17.72 | 0.671 | 5.32 | -43.6 | 2.1 | -16.4 | |
| Immunomedics | IMMU | 26.76 | 0.002 | 4.07 | 30.8 | 1.5 | -9.83 | |
| Incyte | INCY | 69.08 | 1.73 | 15 | -31.5 | 2.2 | 5 | |
| Ionis | IONS | 51.58 | 0.55 | 7.32 | 4.73 | 2.8 | 22.87 | |
| Amicus Ther | FOLD | 12.09 | 0.063 | 2.36 | -20.25 | 1.9 | -22 | |
| Foundation Med | FMI | 137 | 0.179 | 3.95 | 47.65 | 2.5 |
acquired
|
|
| GW Pharma | GWPH | 172.74 | 0.016 | 4.95 | 28.82 | 2.1 | 24.76 | |
| Intercept Pharma | ICPT | 126.36 | 0.158 | 3.89 | 124.24 | 2.4 | 58.15 | |
| Ligand Pharma | LGND | 274.5 | 0.23 | 5.793 | 98 | 2 | 31.98 | |
| Loxo Oncology | LOXO | 170.83 | 0.102 | 5.2 | 97.5 | 1.7 | 0.59 | |
| Neurocrine Bio | NBIX | 122.95 | 0.323 | 11.18 | 55 | 1.6 | 26.47 | |
| Nektar Therap | NKTR | 60.96 | 0.903 | 10.45 | 5.74 | 1.8 | 26.5 | |
| NovoCure | NVCR | 52.4 | 0.217 | 4.92 | 158.1 | 1.8 | 68.5 | |
| Seattle Genetics | SGEN | 77.12 | 0.575 | 12.44 | 37.4 | 2.3 | 18.7 | |
| Serepta | SRPT | 161.5 | 0.24 | 11.11 | 177.2 | 1.7 | 20.76 | |
| Tesaro | TSRO | 39.01 | 0.297 | 2.14 | -48.4 | 2.2 | -11.8 | |
| Ultragenyx | RARE | 76.34 | 0.26 | 3.83 | 54.88 | 2 | 0.3 | |
| Xencor | XNCR | 38.97 | 0.018 | 2.176 | 70.92 | 1.6 | 5.27 | |
| First Trust Arca | FBT | 158.49 | 24.36 | 15.3 | ||||
| iSharesBIO | IBB | 121.94 | 11.5 | 13 | ||||
| NASDAQ-100 | QQQ | 185.79 | 17.23 | 8.5 | ||||
| SPDR S&P | XBI | 95.87 | 9.93 | 1.3 | ||||
| HC SPDR | XLV | 95.14 | 13.79 | 14.2 | ||||
| Data from FinViz | ||||||||
| and Yahoo | ||||||||