Momentous  Biotech for June

Update 6/28...A nice broad rally on Friday included the large cap biotechs with the IBB up 1.73% to $109.82. Even Celgene (CELG) found buyers up 3.6% flirting with the $80 level. The big winner was Vertex (VRTX) up 15.16% to the $170 level on news that a rival Company Galapagos (GLPG) showed disappointing results in a Phase 2 trial for its cystic fibrosis drug. Mid-cap strength was back with leaders: ARNA, BPMC, IMMU, LOXO, SGEN. The XBI regained 1% to $95 off its highs of $101 but still up an amazing 12.1% for June.

Update 6/27… 5 PM EDT Biotech Sell-Off Continues on Profit Taking

The momentum driven, equal weight SPDR S&P Biotech (XBI) took another big hit down 3.22% to $93.62 dropping below the recent breakthrough levels around $96. No specific news but usually biotech trades with the NASDAQ-100 and the QQQ shows a similar pattern. Last week we said follow the technicals and expect a pullback. Macro issues have intervened namely interest rates and trade policy which is still an unknown.

The less volatile IBB was down 2% to $107.34 a good 7 pts. off recent highs and still in a downward trend since February highs.

If you are a trader note how our list of hot mid-caps performed now that the market has cooled down. Today the list was a red screen except Ligand (LGND) up 2.23% on a licensing agreement amendment with WuXi Biologics for antibody discovery services.

GW Pharmaceuticals plc (GWPH) sold off 5.79% despite news Monday that the FDA approved its cannabis- based drug for epilepsy (LGS and Dravet syndrome). The Company believes its cannabinoid drug discovery platform will yield additional products.

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M&A Theme Provides Biotech Momentum: XBI at 52 Week Highs

Biotech Bull Market Intact: Leading Sector YTD

Rayno Top Picks Doing Well:ABBV,BLUE,FMI,XBI

In previous posts over the past two months we have emphasized mid-caps for momentum investing and trading and the XBI (or even the FBT) for weighting of small and mid-cap positions. A watch list of important mid cap companies was provided. Our bullish stance continues and many of our top picks have done well over the years although large cap stocks (see IBB) have lagged. Yesterday the XBI hit a new high above $101 soaring  all the way from $84 in early April when we posted our last Rayno BioBeat article.

Here are some key trends that have driven biotech investing over the past few months:

  • A general market focus on NASDAQ (QQQ) and smaller cap stocks in a sector where emerging biotechnology companies thrive.
  • A gradual realization that ASCO would provide important data for oncology drugs and support use of genomic profiling and biomarkers for personalized medicine.
  • Innovative technology such as gene editing and CAR-T that could revolutionize therapeutics potentially providing longer term cures.
  • Lack of new definitive drug pricing policies from the Trump Administration that would damage the industry business model.
  • M&A and licensing deals that would provide financing and anticipation for stock momentum.

Some of the mid-caps moves in 2018 have been phenomenal but if one had sufficient funds you could buy a basket of them or get lucky owning a few. Or you could take 20 of these picks, apply technically driven software based on MACD and RSI to pick winners. For example among the biggest winners in this mid-cap group near their 52 week highs are: AGIO,ARRY,FMI,FOLD,LGND,IMMU,LOXO and SRPT. The hard part tho is picking the winner and holding for the long term amidst all the volatility.

We will review ETFs by the end of the month as we have in the past and try to explain why the FBT and XBI outperforms other ETFs and funds but primarily their key is equal weighting of mid and small caps.However in a bull market the average investor can do well simply by buying an ETF especially if they want a balanced portfolio including other sectors.

The momentum has been so strong that we expect a pullback and profit taking near term. Follow technicals.

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