Update-1… 11/17…Vertex (VRTX) rises on good volume.Added to small position. Good value on fwd PE; look for an upgrade or a deal. Strong CF franchise but needs R&D milestone hit.

Large Cap Biopharmaceuticals Metrics and Review

  • Stock Performance was mixed across the sector so stock picking was key.
  • The biotech sector underperformed as shown by the IBB flat YTD.
  • Our top picks were Abbvie (ABBV), Merck, Regeneron (REGN) and Roche (RHHBY).

Throughout 2021 we emphasized large cap biopharmaceuticals as a core holding in your healthcare portfolio. We developed this model with diversification from medtech and life science tools.When the antiviral news broke we were holding a little Merck and Pfizer which only recently caught up. The following large caps are at or near 52 week highs: ABBV, GSK, LLY, PFE and RHHBY. Good performance was achieved in slower growth value plays with good dividends: GILD, GSK. We traded LLY which is the best performer in 2021 but has become very expensive with a Price to Sales of 9.26 and a forward PE of 31.72. The LLY chart shows a double top at $270

Laggards were BIIB still up YTD despite selloff from Aduhelm AD drug; and VRTX which is tradable for a potential deal. Amgen is another laggard down 8% YTD because of lackluster growth,

Today JNJ announced a split of the Company separating its legacy consumer products from higher growth growing biopharmaceutical and medtech products.The response was good but the stock rose only 1.34% to the $165 level .JNJ was $180 in August.

We will update this post through January 2022 at the time of the JPMorgan Healthcare Conference.

1/15/18 11/11/21 11/1/19 2021 YTD FWD Analyst %
$B P/S PE Recom Div
Abbvie ABBV 100.000 116.63 81.75 206.2 8.85 3.73 8.4 1.9 4.46
Alexion*(ALXN) ALXN 123.000 182.5 109.38 40.33 n/a 4.56 9.38 2.2
*acquired by AZN
Amgen AMGN 185.000 211.56 221 119.2 -8 4.69 11.7 2.5 3.33
AstraZeneca* AZN 35.000 62.92 40.34 196.4 25.9 6.76 15.81 1.6 2.23 see ALXN
Biogen BIIB 336.000 266.57 299.2 39.16 8.87 3.55 14 2.3
Bristol Myers* BMY 63.000 59.19 57.16 131.4 (4.4) 2.88 7.56 2 3.31
Celgene* (BMY) CELG 106.000 n/a 108.53 77 n/a 4.69 8.7 n/a
*acquired by BMY
Gilead Sci GILD 79.000 67.43 64.66 84.6 12.18 3.08 9.93 2.4 4.21
GlaxoSmithK GSK 38.000 43.23 45 108.76 17.47 2.39 13.51 2 5.02
Eli Lilly LLY 85.000 262.6 113 251.2 51.55 9.26 31.72 2.2 1.29
Merck MRK 59.000 84 84.94 212.2 7.64 4.95 11.48 2 3.09
Regeneron REGN 367.000 626.6 310.48 70.9 29.7 5.24 13.61 2
Vertex VRTX 158.000 185.9 215.21 48.6 21.35 6.81 13.95 2
XBI 124.62 83.66 -10.28
IBB 169.4 109.85 1.27
FBIOX 22.45 20.26 -13.07
XLV 133.69 94.87 17.37
XPH 50.06 39.47 -2.23
QQQ 368.82 201.23 24.5

Pin It on Pinterest