• Update-1 11/25/19... Rally right on track driven by NVS/MDCO deal, new product surge and cheap money from FED.
  • As we said many time on this site XBI is the bellwether up 4.25% today  (UP 13% in one month) as biotech stocks broke out last week. IBB up 2.46%.
  • We hold many winners today: ALNY, AMRN, DRNA, FBIOX, GILD, SGMO VCYT XBI etc.
  • The Medicine Company deal announced with  Novartis purchase for $9.78B.RNAi drugs are in a very hot sector: ALNY, ARWR , DRNA, etc.
  • Gene therapy stocks are hot: BLUE,CRSP, EDIT, NTLA  etc.
  • Mid-caps surged: ARNA, ASND, BPMC, ICPT, MRTX, SGEN, etc.
  • Laggard large cap Alexion (ALXN) up 2.95% to $114.30; laggard GILD up 3%.
  • CCXI from $8 to $35 on 5a receptor data for ANCA vasculitis! Microcaps on the move

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Sentiment Shift Boosts Biotech Stocks in late 2019: IBB up 18.37% , XBI up 20.97%.

Rotation into Healthcare Stocks is in the Sixth Week and XLV is up 15.33% YTD.

Large Cap Biopharmas Lead the Way with Good Earnings and Guidance

2019 was a volatile year for healthcare stocks until early October when a reversal began as Q3 earnings allayed investor fears.The overall healthcare sector was flat as of mid-April wracked by political posturing with promises of lower drug prices and “Medicare for All”. As the hard rhetoric faded and sales growth plus value became a more realistic scenario for 2020 the healthcare markets recovered. Large cap drug stocks now can offer investors below market PEs in 15 range with attractive dividends.

Despite the good performance of biotech ETFs gains investors did better with the S&P 500(SPY) up 25.88% YTD and the NASDAQ-100 (QQQ) was up 31.4% YTD.

A sentiment shift in biotech was helped by FDA approvals and breakthrough technologies such as CAR-T and gene editing. Moreover a supportive FED indicated a low interest rate scenario for months to come favoring a boost in M&A.

A snapshot of ETFs and Funds in healthcare and life science stocks shows the breadth of the rally with MedTech a leader (IHI).

Name Symbol Sector Price % Perf
ETF or Fund 11/22/19 YTD
First Trust Arca Bio FBT Biotech large 141.86 14.35
iShares NASDAQ Bio IBB Biotech large 115.41 18.37
iShares U.S Healthcare IHF Providers large 193.69 20
iShares U.S, Med Dev IHI Med Tech, large 254.63 30.93
SPDR S&P biotech XBI Biotech equal wt 88.14 20.97
Healthcare Select SPDR XLV Large cap divers 98.26 15.33
Fidelity Select Bio FBIOX Divers Bio 21.43 25.17
T.RoweP Health Sci PRHSX Divers Bio 82.33 22.86
Fidelity Select Med Tech FSMEX Med tech large 58.39 23.5

Our focus has been to update the broad themes with deals and earnings news that tends to pick up in the fourth quarter.

Our large cap biopharma picks –ABBV,BMY,CELG,RHHBY-have done well as you can see from the is chart (last updated 11/1/19).  Two of the large cap laggards have shown big gains in November : BIIB up 11% and REGN up 20%.

COMPANY Ticker Price 2017 Price Price MCap
% Perform
1/15/18 Rev$B 12/18 11/1/19 2019 2019 FWD Analyst %
$B YTD P/S PE Recom Div
Abbvie ABBV 100.340 27.27 92.19 81.75 121 -10.85 3.71 8.55 2.1 5.24
Alexion ALXN 122.710 3.47 97.36 109.38 24.42 7.5 5.16 9.77 1.8
Amgen AMGN 185.040 23 194.67 217.95 130.55 11.13 5.58 13.8 2.3 2.66
Biogen BIIB 335.950 11.84 300.92 299.2 53.9 -1.58 3.79 9.09 2.7
Bristol Myers BMY 62.810 19.92 51.98 57.16 93.84 9.42 3.93 9.03 2 2.87
Celgene CELG 106.000 12.5 64.09 108.53 76.7 62.11 4.69 8.7 2.9
Gilead Sci GILD 79.020 27.48 62.55 64.66 82.12 0.43 3.68 9.3 2.1 3.9
Merck MRK 58.660 39.8 76.41 84.94 221.88 14.64 4.83 15.26 1.8 2.59
Regeneron REGN 366.960 5.52 373.5 310.48 33.07 -17.76 4.57 12.37 2.5
Vertex VRTX 158.000 2.3 165.71 200.94 50.25 19.14 13.88 30.48 2
XBI 71.75 83.66 16.6
IBB 96.43 109.85 13.92
FBT 124.2 132.92 7.02
FBIOX 17.74 20.26 14.21
XLV 86.46 94.87 9.66
XPH 39.47 7.78

The sentiment shift is bullish near term assuming we do not get major flack from macro events such as geopolitical turmoil and China trade setbacks.   The wild card for healthcare stocks on the downside could be political like repeal of the ACA or legislation on drug pricing.Moreover healthcare costs are rising and unsustainable long term.  

With low interest rates CEOs see more opportunities for M&A than R&D or CAPEX investment. 

 Drivers through January are: M&A, major clinical (ASH)  and banker (JPM) conferences , FDA product approvals and clinical trial updates.Stock portfolios should remain overweight a diversified healthcare portfolio including biotech stocks.

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