9/8/23…215 EDT B.of A. upgrades laggard Gilead Sciences (GILD) stock rises 2.5% to $75 handle. Div. 3.96%,FWD PE 10.45, P/S 3.44.

9/8/23…10:45 EDT.Markets follow 10 yr yield with rally at 4.22%.  As yield rises markets weaker. S&P at 4468 up 0.38%. As yield rises to 4.30% equities are weak.

Markets primarily trading on technicals with healthcare gains as techs weaken, IBB at $127 looking for $130. XLV trying to hold $130. Energy continues strong today.(charts below).

9/6/23….MedTech running today see one upgrade on SYK from BofA, but many large caps look strong: ABT, BSX, GKOS and ZBH up 4.55%.Large cap biopharma still a bit hungover from drug pricing legislation.

Healthcare stocks Have Value But Where?

  • Large Cap Biopharmaceuticals Still  Look Good.
  • SMID Biotech Still Tradable with Dealmaking Potential.
  • Stock Picking Is More Important than ETFs.

Many healthcare stocks may be defensive in nature but if you are overweight the basic plays like the XLV or biotech funds like the Fidelity Biotechnology Fund (FBIOX) you are trailing the market over the past two years. The S&P 500 (SPY) is up almost 18% in 2023 while the XLV lost 1.68% despite being up almost 44% over 5 years.There are several  reasons for this but what has happened over the past two years is that the Biden Administration wants to reduce healthcare expenses by lowering drug costs. And the FTC has been fighting M&A so deals have been slow. Moreover tech stocks like semiconductor chips and IT software have boomed as data is ever important.Moreover the disruption of markets caused by the pandemic reduced elective surgeries and created a short term boomlet in vaccines. Many of these healthcare technology stocks reached a peak in mid-2021 and have yet to recover.

Large cap biopharmaceuticals did outperform the market because of strong balance sheets, dividends and new products but only if you picked the right stocks. The leading biopharmaceutical stocks YTD are LLY up 52% YTD, VRTX up 21.58% and REGN up 15.27%. Over 5 years the numbers look even better with returns for Lilly (LLY) a huge 427%, Regeneron (REGN) 104% and Vertex(VRTX) 90%. What these companies have in common are innovation in R&D with new blockbuster drugs. Merck (MRK) also had a great 5 year performance with products in oncology.And the valuations for most of these large caps are attractive with FWD PEs and Price to Sales.

Do We Need a Weaker Economy for Healthcare stocks to Outperform?

Last week healthcare stocks lagged again as investors’ moved broadly into other sectors: energy, tech, industrials and materials. But with drug pricing legislation targets revealed and a “go ahead” by the FTC for the Amgen/Horizon acquisition, we could see a pick-up in fourth quarter deal making.

Another sector of healthcare stocks hit hard in 2023 was the US Healthcare providers (IHF) down 7.34% YTD, UNH is flat YTD and CVS down 29% YTD!

SMID caps lagged mirroring the Russell 2000 (IWM). Small cap growth is a favorite area for speculation as tracked by the XBI. Despite some hot streaks in Q2 2023, the  momentum did not last and the XBI is down YTD  .Its been a roller coaster year for small caps.

Many investors consider 2023 to be a great year considering the S&P 500 is up 18%. Treasuries offer a 5% yield so investors can protect their gains with blue chips (JNJ,MRK) and cash. Or with a more aggressive approach add to MedTECH assuming trends improve with am ETF like the iHi or lagging blue chips ABT, BDX and SYK. Experienced biotech traders can play SMID biotech with the IBB, consolidating in the $125-130 zone.

In the meantime we watch the FED hoping rates don’t go much higher than one more 0.25% move up in rates. For now some economists are expecting a soft landing for the economy even if rates are higher for longer but inflation must stay low. Follow 10 yr yield.

Model
PORTFOLIO *
2020 2020 2020 2021 2022 2023 5 yr % tot ret
Stock/ETF Ticker Price Wgt Price Price Price Price
10/25 % 12/31 % Perf 12/31/21 12/31/22 9/3 % Perf %Perf %
P 30 days YTD
iShares NAZ Bio IBB 136 20 151.5 25.7 152.62 130.55 130 153 0.97 6.4
iShares Russell 2k IWM 163 10 196.4 18.3 222.45 174.36 190.85 (3.510 9.46 10.31
Merck* MRK 80 10 81.77 -10 76.64 110.81 109.84 4.33 -1 67.83
United Health UNH 330 10 350.7 27.19 502 530.27 476.24 -5.65 -0.17 77.4
SPDR S&P Bio XBI 117 10 140.8 48 111.96 83 81.13 -2.61 -2.25 -18.98
Healthcare SPDR XLV 108 20 113.4 14.71 140.89 135.88 133.57 -1.68 43.96
T.Rowe Hlth Sci PRHSX n/a 5 99.65 n/a 104 89 89.76 0.3 7.43
iShares U.S MedT IHI 50 10 54.83 65.85 52.57 52.59 -5.55 43.52
MedTech* ABT new 5 123.5 127.46 109.83 102.85 -6.95 -6.32 53.87
peak yr
Tracking Comp
ARK Genomic ARKG 93.26 61.24 28.23 32.61 -11.96 15.52 -5.34
Direx3X Bull LABU 7.66 5.26 -9.78 -25.6 -95.1
FIDO Biotech FBIOX ** 25.18 19.35 16.04 16.66 (0.720 2.33 -32.19
FiDO MEDtech FSMEX 76.15 83.18 61.58 62.46 -2.37 1.43 13.73
DOW DIA 310 363.32 331.34 348.98 -2.03 5.33 34.3
S&P 500 SPY 379 475 382.41 451.19 -1.16 17.98 55.42
NASDAQ-100 QQQ 315 397.85 266.33 377.59 91.36) 41.8 102.3
Technology SPDR XLK 128.93 161.97 124.44 176.2 -1.37 41.59 133.07
Top Biopharmas 2022 9/3 5 yr % total
Abbvie ABBV * 161.64 148.2 (0..23) -8.3 54.41
Astra Zeneca AZN * 68 68.14 -4.63 0.5 77.73
Bristol Myers Sq BMY 71.05 62.02 0.8) -13.8 2.43
Gilead Sci GILD 85.39 76.65 1.28 -10.72 1.21
Eli Lilly LLY * 447.71 557.11 22.96 52.28 427.32
Merck MRK * 110.95 109.84 4.33 -1 67.83
Pfizer PFE * 51.24 35.78 -0.48 -30.17 -9.17
Regeneron REGN * 725 831.63 12.52 15.27 104.46
Vertex VRTX * 288.78 351 0.97 21.58 90.4

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