Healthcare Playbook -JPM Day One 1//24

Momentum resumed in many small cap biotech stocks today helped by dealmaking. The IBB was up 2.4% to $139.39 and the equal weighted small cap XBI was up 4.6% to $93.42. Among the big movers on our SMID Focus list below are: Caribou (CRBU) up 19.09% to 5.74, CRSPR Therapeutics (CRSP) up 3.33% to $62.69, Cryoport (CYRX) up 4.98% to $16.22, Geron (GERN) up 6.97% to $2.15, 10X Genomics  (TXG) up 3.43% to $53.41, Veracel (VCEL) up 6.98% to $34.79, VeraCyte (VCYT) up 13.1% to $29.10 . And tech stocks also resumed their climb with the QQQ up 2.7% to $404.95.

If the FTC lets the market do its dealmaking then smaller companies can get funding. That’s the dynamic.

Cytokinetics (CYTK) up another 18%++on Novartis buyout talks, after recent Phase 3 heart drug readout. ( How could I miss this one?)

Gene therapy stocks remained strong with green screen: CRSP FOLD NTLA SRPT. Here is CRISPR update

Obesity bandwagon: Pfizer still in plus Roche and Amgen.

1/9 update: ILMN up 4% on prelim earnings.

Medtronic (MDT) gets FDA approval for advanced DBS neurostimulator, stock up 2.36%.

Data as of January 7, 2024.

P 1/20/23 % Perf 2/4/23 12/24/23 Perf %
Company Ticker $ P % week P 4 wks YTD % REC 1/7/2024
P
Acumen Therap ABOS 5.29 3.57 51.27 -33.89 1.5 4.02
Catalyst Pharma CPRX NEW 16.1 19.62 16.58 19.62 -10.86 1.8 14.57
Caribou Biosci CRBU NEW 6.29 20.55 6.17 8.44 -0.175 1.8 4.82
CRSPR Therap CRSP 49.61 -25 55.27 4.72 63.67 -9.68 56.63 2.3 60.67
Cryoport CYRX 21.75 -42.34 25.24 9.41 16.09 14.76 -7.26 2.3 15.45
Evolent Health EVH 30.83 13.74 31.96 2.21 32.08 8.56 14.25 1.7 32.36
Geron GERN 3.19 9.24 3.22 3.59 2.29 17.44 -5.37 1.5 2.01
Hologic HOLX 79.66 22.41 84.68 2.28 71.04 -1.58 -5.04 2.4 72.95
Immatics IMTX NEW 9.3 9.9 20.88 13.66 1.5 10.42
Pacific Biosci PACB 11.29 55.68 11.58 -1.7 8.59 28.4 5 2.2 9.4
Quidel/Ortho QDEL 88.13 -11.56 89.7 3.93 73.98 7.19 -13.65 2 73.75
Supernus SUPN 40.3 12.3 41.61 2.29 29.23 6.04 -18.05 2 27.43
Twist Biosci TWST NEW 12/2 18 3.76 54.39 34.03 2.2 33.98
10x Genomics TXG NEW 12/2 47.84 56.58 30.52 55.27 2.3 51.64
Vericel VCEL NEW 31 34.75 -2.09 31.93 1.5 32.52
Veracyte VCYT 24.89 39.43 26.67 2.46 28.27 8.23 19.13 2.1 25.73
SPDR Biotech XBI 86.99 14.75 90.39 1.12 87.62 20.36 5.57 n/a 89.3
wildcard
ArkGenomics ARKG NEW 35.28 32.81 18.88 16.22 n/a 31.61
Becton-Dickinson BDX old pick 240
Cerevel CERE acquired 42.26
Cytokinetics CYTK missed 93.73
12/24/23 5 yr
iShares CoreS&P IJR 108.34 12.96 14.48 63.24 104.39
iShares Russell IWM 201.48 13.11 15.55 56.95 193.25
iShares BIO IBB 133.77 12.68 -1.89 47.23 136.12
NASDAQ-100 QQQ 408.38 4.7 53.36 176.74 396.75
HealthcareSPDR XLV 135.02 3.52 63.3 139.12
T.RowePrice PRHSX 86.84 3.67 -3.32 36.99 88.33
iShares MED Dev IHI 53.65 7.34 2.05 70.63 53.25

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