Update-2 Jy 22 Catch-up Rally last week continues in MedTech and Diagnostics: ABT our top pick up 5.89% to $114.29,  DHR up 6.38% to $255.88,IHI up 1.32% to $57.59,TMO up 6.89% to $562.  New Pick Becton Dickinson (BDX) up 2.1% to $264.84.  Earnings coming next week for many MedTech stocks.

Stocks to Watch

HOLX QDEL VCYT strong holds from our Mid-cap portfolio.

ILMN new long trade at $186.

TOP MedTech Funds Picks: FSMEX and PRHSX.

AACC Meeting this week in Anaheim. I am traveling on vacation to Boston so cannot attend this meeting but will post news regarding our portfolios in Life Science Tools and Diagnostics.

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Update-1 JY 20 P EDT Catch-up rally for lagging large cap healthcare stocks helped by JNJ results.

The brief reversal continued today with a rotation out of technology and comm services sector and into energy and healthcare stocks. Large cap biopharmas soared: ABBV, AZN, GILD,MRK, REGN, VRTX even BMY? MedTech was strong: ABT, BDX, BSX and IHI.

JNJ was up 6.2% on an earnings beat and guidance increase. Kenvue split-off coming. The XLV hit a recent low on JY 13  at the $129 handle and is now $135. one year low was 9/26 around $121.

This strength in large cap defensive healthcare stocks in a weak market could mark a pivot away from momentum.

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Last week saw a broadening of the rally as many top sectors were up over 3%. But healthcare was among the laggards up only 0.7%. Of course healthcare is a defensive sector and this is a hot market. As we come up on Q2 earnings not much good has happened in the healthcare sector until United Health on Friday. We’ve also seen some new small cap biotechs sizzle with extreme volatility.  Recursion pharmaceuticals (RXRX) up 78% on $50M Nvidia drug discovery deal. As predicted AI meets biotech. Trading rallies for sure as more AI plays  are likely. And Caribou Sciences raised more money after a $25M equity deal from Pfizer.

And Pre-market today we see a few  small cap biotech movers: Acumen  Pharmaceuticals (ABOS) and BridgeBio Pharma (BBIO).

Let’s start with an update from my last Healthcare sector review from June 21.

  • Major ETFs:  IBB flat to down from $131, XBI down to $84.42 from $87 handle.
  • Healthcare ETF XLV:  flat but buoyed by UNH earnings beat today, stock was up over 7% to $480 on earnings UNH showed balanced growth of 16% with operating earnings growth of 13% EPS $5.82.. Cost concerns due to more procedures were allayed.
  • U.S. MedTech (IHI) slight improving trend up 3.63% over one month to $56.84
  • T.Rowe Price (PRHSX) is flat over one month ending at $90.03.We expected better from this fund.
  • ARK Genomic Rev (ARKG) up 5.1% over one month to $36.26 but off mid June lows.

We Need Help from Smaller Caps-Genomics and Gene Therapy

As you know by now the best performing ETF has been the QQQ up 42.36% YTD and still strong up 3.6% for the month after a brief ow in the $357 level. So you see the issue that the TECH sector led by he “Magnificent Seven” now infused with the AI theme creates momentum that crowds out biotech sentiment. Also note that the Renaissance ETF (IPO) another measure of speculative bullish sentiment is up 42%YTD.

Looking at our old SMID Portfolio here are several stocks that still look like good holds: ABOS  GERN HOLX  PACB VCYT. There is good tape activity in many speculative life science stocks for example in the ARKG fund. Among the Top Ten holdings of ARKG that were also in our SMID Portfolio are : CRSP NTLA PACB.

T.Rowe Price Health Sciences Fund (PRHSX) performance was hurt by weakness in AZN MRK REGN and major device players like DHR and TMO. We expect these top picks to do well in the months ahead. Without growth in major tools and diagnostics players biotech stocks will lag. But several genomics tools stocks are trading near 52 week highs: Exact Sciences (EXAS) Pacific Biotech (PACB) and 10x Genomics (TXG). And of course the behemoth of DNA sequencing Ilumina (ILMN) has been mired in the battle over their GRAIL acquisition,  but we see it as a speculative long trade.

MEDTech is a core Position for every Healthcare Portfolio

We have owned Becton Dickinson (BDX) for more than ten years with a 10x return but have never covered the stock. But the time looks right to recommend the  position.The Company is broadly diversified in medical supplies, equipment, tools and diagnostics.The stock trades currently at $259 with roller coaster technicals over 12 months and trades at a Fwd PE of 18.89. The P/S is a reasonable 3.93 and the stock has received five upgrades since 1/23 with a recommendation score of 2.10.

We recommended Abbott Labs (ABT) a few months ago at price of about $110 but the stock has been weak due to issues with the baby formula business.The worse should be over for the stock and it remains a strong hold at price of $108.

The IHI is trending up so make thisU.S. Medical Devices ETF your core position until we get through Q2 earnings. An alternative would be FSMEX with 9%+ returns over five years.

Large CapBiopharmaceuticals-Underperforming

We will update our performance metrics after Q2 earnings. Maybe you are ready to buy into recent weakness in AZN and REGN. Most of these large caps have taken a hit in 2023 but the top performers that we own are : LLY MRK VRTX.

Here is our Model Healthcare Portfolio as of June 30, We will update on July 31.

Long ABT AZN, ,BDX,FSMEX, IHI,MRK, PRHSX, UNH, XBI.

Model
PORTFOLIO
2020 2020 2020 2021 2022 2023 5 yr Total
Stock/ETF Ticker Price Wgt Price Price Price Price
10/25 % 12/31 % Perf 12/31/21 12/31/22 6/30 % Perf %Perf %
P Month YTD
iShares NAZ Bio IBB* 136 15 151.5 25.7 152.62 130.55 126.96 0.54 -3.3 15.61
iShares Russell 2k IWM 163 10 196.4 18.3 222.45 174.36 187.27 7.77 7.4
Merck* MRK 80 10 81.77 -10 76.64 110.81 109.32 -1.26 -1.47
United Health UNH 330 10 350.7 27.19 502 530.27 480.64 -1.35 -9.34
SPDR S&P Bio XBI 117 15 140.8 48 111.96 83 83.2 -0.86 0.24 -12.6
Healthcare SPDR XLV 108 20 113.4 14.71 140.89 135.88 132.73 3.83 -2.3 59
T.Rowe Hlth Sci PRHSX n/a 5 99.65 n/a 104 89 90.77 2.9 1.06
iShares U.S MedT IHI 50 10 54.83 65.85 52.57 56.46 6.71 7.4
MedTech* ABT new 5 123.5 127.46 109.83 109.02 6.88 -0.7
Tracking Comp
ARK Genomic ARKG 93.26 61.24 28.23 34.09 7.78 20.76
Direx3X Bull LABU 7.66 5.92 -5.13 -16.27
FIDO Biotech FBIOX 25.18 19.35 16.04 16.6 0.3 1.97
FiDO MEDtech FSMEX 76.15 83.18 61.58 65.42 5.02 6.24
DOW DIA 310 363.32 331.34 343.85 4.35 3.78
S&P 500 SPY 379 475 382.41 443.28 6.09 15.91 63.4
NASDAQ-100 QQQ 315 397.85 266.33 369.42 6.16 38.73 115.22
Technology SPDR XLK 128.93 161.97 124.44 173.86 5.83 39.71
Top Biopharmas
5 yr % Total
Abbvie ABBV 161.64 134.73 -2.34 -16.63 45.42
Astra Zeneca AZN 68 71.57 -2.07 5.56 103.85
Bristol Myers Sq BMY 71.05 63.95 -0.76 -11.12 15.56
Gilead Sci GILD 85.39 77.07 0.17 -10.23 8.79
Eli Lilly LLY 447.71 468.98 9.2 28.19 449.61
Merck MRK 110.95 115.39 4.51 4 99.22
Pfizer PFE 51.24 36.68 -3.52 -28.42 6.56
Regeneron REGN 725 718.54 -2.31 -0.41 108.28
Vertex VRTX 288.78 351.91 8.76 21.86 197.05

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